Start with a federal Employer Identification Number if you don’t already have one. Apply through the IRS website and you’ll get it immediately. You cannot register with Michigan or process payroll without it.

Register with two Michigan agencies. The Michigan Department of Treasury handles income tax withholding. The Michigan Unemployment Insurance Agency handles unemployment tax. Both registrations can be completed online. You’ll receive account numbers for filing and paying these taxes going forward.

Collect paperwork from every employee before their first paycheck. Form W-4 determines federal and Michigan income tax withholding based on the employee’s filing status. Form I-9 verifies employment eligibility. Keep these documents organized because you may need them for years.

Choose how you’ll actually run payroll. Manual calculation works if you have one or two employees and don’t mind researching tax tables and deposit rules. Payroll software like Gusto or QuickBooks Payroll automates calculations, tax deposits, and quarterly filings. Payroll system setup through a professional ensures everything is configured correctly from the start. Full outsourcing means you just approve hours and someone else handles the rest.

Understand deposit schedules before you run your first payroll. Federal payroll taxes deposit either monthly or semi-weekly depending on your total tax liability. Michigan withholding follows a similar schedule. Late deposits trigger penalties immediately, and the IRS does not send reminders.

Workers’ compensation insurance is required in Michigan before you hire your first employee. Rates vary by industry and your claims history. This is not optional and the state enforces it.

File quarterly reports on time. Form 941 goes to the IRS reporting wages and taxes withheld. Michigan requires quarterly wage reports to the Unemployment Insurance Agency. Miss deadlines and penalties start accumulating.

The good news for Metro Detroit businesses is that most cities in Macomb County and the surrounding area do not have local income taxes you need to withhold. This simplifies things compared to states where every municipality has different requirements.

The setup process is manageable if you’re careful, but the ongoing compliance is where mistakes happen. Incorrect withholding means employees owe money at tax time. Missed deposits mean penalties. Wrong classifications mean back taxes and audits. Many small business owners work with a Metro Detroit bookkeeping service to handle payroll correctly from the beginning rather than fixing problems later.